Life Science Filter

Protecting Life with Biosecurity Filtration

Depth Filter ZetaCARE

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    Feature_Tec ZetaCARE depth filter boasts a stable, reliable, and powerful liquid clarification capability. The filter media is composed of wood cellulose, inorganic filter aids, and charged resins through a multi-step composite process. 
    The three-dimensional interwoven structure within the filter media effectively removes particles, cell debris, and other insoluble impurities, providing the first line of defense for efficient liquid clarification. 
    The uniformly distributed charges can effectively remove residual DNA and host cell proteins (HCP) and other soluble impurities, providing a second line of defense for efficient liquid clarification. 
    The dual overlapping protection ensures robust support for efficient liquid clarification, reducing the downstream purification load, helping customers shorten process times, lower production costs, and increase economic benefits.

     

     

    Features

    • Filter media composed of wood fibers and inorganic filter aids
    • Three-dimensional structure with progressively finer filtration layers.
    • High throughput, high capacity, and high retention rate.
    • Balanced pressure control ensures consistent precision across batches, enabling reliable operational processes.
    • Available in both positively and negatively charged versions to meet diverse customer clarification needs.

     

     

    Typical applications

    • Clarification filtration of fermentation broths or cell culture fluids
    • Clarification filtration after virus inactivation
    • Clarification filtration of blood and serum products
    • Filtration of enzyme preparations
    • Clarification filtration of plasmids or viruses

     

     

    ZetaCARE Process Development (PD)

    • Filtration Layer‌: Double Layer
    • Housing Material‌: PP
    • Filter Sheet‌: Cellulose, Filter Aids, Resin
    • Support Layer‌: PP
    • O-Ring‌: /
    • Effective Filtration Area‌: 23cm²
    • Dimensions (cm)‌: 8.9×6.6×4.1
    • Outlet, Vent Ports‌: Luer Ports: Polycarbonate
    • Max. Operating Pressure‌: 3.5bar @ 20°C
    • Max. Forward D.P.‌: 2.1bar @ 20°C
    • Max. Reverse D.P.‌: 1.0bar @ 20°C
    • Sterilization Tolerance‌: Integrity remains unchanged after 2 times of 121°C for 60 minutes.
    • Indirect Food Additives‌: All materials comply with FDA standards for indirect food additives per 21 CFR 177-182.
    • Toxicity‌: All materials comply with the current USP<88> Class VI plastic biocompatibility tests.
    • Bacterial Endotoxins‌: Filter Media: <0.25 EU/mL by USP<85> LAL test method.
    • Conductivity‌: After steam sterilization (121°C for 60 minutes, once): Single Layer: Conductivity <20 μS/cm after rinsing with 50 L/m² of purified water. Double Layer: Conductivity <20 μS/cm after rinsing with 100 L/m² of purified water.
    • TOC‌: After steam sterilization (121°C for 60 minutes, once): Single Layer: TOC <5ppm after rinsing with 50 L/m² of purified water. Double Layer: TOC <5ppm after rinsing with 100 L/m² of purified water.
    • Non-volatile extractable mass‌: After soaking in DI water for 24 hours, the non-volatile extractable mass for the small-scale test is measured to be between 630 and 1251 mg/m².

     

    ZetaCARE Lab-Scale (LS)

    • Filtration Layer‌: Double Layer
    • Housing Material‌: PP
    • Filter Sheet‌: /
    • Support Layer‌: /
    • O-Ring‌: /
    • Effective Filtration Area‌: 270cm²
    • Dimensions (cm)‌: 22×14×7.9
    • Outlet, Vent Ports‌: 6mm Hose Barb
    • Max. Operating Pressure‌: 2.1bar @ 20°C
    • Max. Forward D.P.‌: 2.1bar @ 20°C
    • Max. Reverse D.P.‌: 2.1bar @ 20°C

     

    ZetaCARE Production-Scale (PS)

    • Filtration Layer‌: Double Layer
    • Housing Material‌: Glass Fiber-Filled Polypropylene
    • Filter Sheet‌: /
    • Support Layer‌: /
    • O-Ring‌: Silicone
    • Effective Filtration Area‌: 0.11m² / 0.55m² / 1.1m²
    • Dimensions (cm)‌: 61×33×3.4 / 61×33×7.4 / 61×33×12.4
    • Outlet, Vent Ports‌: Flat Seal (TPE)
    • Max. Operating Pressure‌: 3.5bar @ 20°C; 1.0 bar @ 80°C
    • Max. Forward D.P.‌: 2.1bar @ 20°C; 1.0 bar @ 80°C
    • Max. Reverse D.P.‌: 2.1bar @ 20°C。
Depth Filter ZetaCARE
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  • Depth Filter ZetaCARE

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