Life Science Filter

Protecting Life with Biosecurity Filtration

LOPAC SP Sterilizing Filter

  •  

    LOPAC SP series filter is made of modified polyethersulfone membrane (PES) with good hydrophilicity and low protein adsorption. It is suitable for sterilizing filtration of process fluid, buffer and column protection.

     

    Product Feature

    • Reliable bacterial retention

    • Excellent chemical compatibility (pH 1-14)

    • Unique double layer membrane design for increased loading capacity

    • Rugged construction for multiple sterilization cycles

     

    Applications

    • Sterilization filtration of cell culture media
    • Buffer filtration
    • Pre-Column / Pre-Ultrafiltration Protective Filtration
    • Sterilization Filtration of end products

LOPAC SP Sterilizing Filter
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  • LOPAC SP Sterilizing Filter

Product Parameters

  • Filter Type

    dish filter

    capsule filter

    Cartridge filter

    Nominal Size (inches)

    φ50mm

    S

    2.5

    5

    10

    Specifications

    5

    10

    20

    30

    Filtration area
    (M²)

    single layer

    15cm ²

    180cm ²

    0.073

    0.23

    0.63

    D63
    D70

    0.23
    0.3

    0.45
    0.6

    0.9
    1.2

    1.35
    1.8

    double layer

    15cm ²

    160cm ²

    0.065

    0.2

    0.6

    D63
    D70

    0.23
    0.3

    0.45
    0.6

    0.9
    1.2

    1.35
    1.8

    filter pore size

    0.22μm

     

    Structure material

    Support layer: Polypropylene (PP)
    Housing/End caps/Fins: Polypropylene (PP)
    Interface: Polypropylene (PP),222/226 with built-in stainless steel reinforcement option
    Sealing ring: silicone rubber/EPDM/fluorine rubber/fluorine rubber
    Hot melt technology: hot melt sealing without adhesive
    Membrane material: hydrophilic polyethersulfone (PES)

     

    Maximum operating differential pressure

    Forward

    2bar(29psi)@ 20 ℃

    L 、 M:5bar(72.5psi)@ 20℃
    3bar(43.5psi)@50℃

    5bar(72.5psi)@25℃
    2bar(29psi)@ 80 ℃

    S:4bar(58psi)@20℃

    Reverse

    2bar(29psi)@ 20 ℃

    2bar(29psi)@ 20 ℃
    1.5bar(22psi)@50℃

    2bar(29psi)@ 25°C

    Sterilization method

    Withstand high pressure steam sterilization
    and radiation-resistant sterilization

    High pressure steam sterilization: 134°C * 30min * 25 times
    Irradiation sterilization:<50 kGy

    High pressure steam sterilization: 134°C * 30min * 25 times
    Online steam sterilization: 134 ℃ * 30min * 25 times (△p≤ 0.3bar)

    bacterial interception

    > 10cfu/cm2. B.diminuta (ATCC19146)

    biological safety

    The structural components of this filter element meet the current USP<88> grade VI material biosafety requirements

    Cleanliness

    Meet the requirements of FDA21CFR211.72 and 210.3 (B)(5)(6) for non-fiber shedding filters, and the level of insoluble particles in the flushing fluid meets the requirements of USP<788>

    Toxicity of ingredients and materials

    Comply with USP<88> Response Test for Class V Plastics

    endotoxin

    The endotoxin level of the filter element flushing fluid tested by gel method <0.25EU/mL meets the requirements of USP<85>

    integrity

    100% of each cartridge/filter passed the integrity test before leaving the factory

    Production Environment

    All in one hundred thousand clean workshop production

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